The World Anti-doping Agency (WADA) prohibited list has contained higenamine since 2017 as banned at all times in the beta-2 agonist (S3) category, with a reporting level of 10 ng/ml for the free parent form in urine.
It's important to remember just because a substance is banned for use in sport doesn't mean it can't be sold. Higenamine is still present in some nutritional supplements marketed for stimulant and/or weight loss.
In this study, an investigation into the content of beetroot or beetroot-containing foodstuffs and supplement products was conducted. The results in this paper demonstrate the first reported evidence of a link between beetroot and this WADA prohibited substance.
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